SCHEMBL9157404

SCHEMBL9157404

Oc1ccc(N2C=CN(c3ccc(O)cc3)C=C2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
KMT2A Q03164 3/20 0.50
ALOX15 P16050 3/20 0.50
ALDH1A1 P00352 3/20 0.50
MEN1 O00255 2/20 0.50
CA3 P07451 2/20 0.50
CYP3A4 P08684 2/20 0.50
HIF1A Q16665 2/20 0.50
HSD17B10 Q99714 2/20 0.50
CA14 Q9ULX7 2/20 0.50
KDM4E B2RXH2 2/20 0.50
NPC1 O15118 1/20 0.50
CA12 O43570 1/20 0.50
GMNN O75496 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
LMNA P02545 1/20 0.50
TYR P14679 1/20 0.50
HPGD P15428 1/20 0.50
NFKB1 P19838 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL18095025 0.71 HSD17B10 (0.80) MAPTKMT2AALOX15ALDH1A1MEN1
Hydroquinone SCHEMBL11511669 0.71 ALOX15 (1.00) MAPTKMT2AALOX15ALDH1A1MEN1
Hydroquinone SCHEMBL460669 0.71 ALOX15 (1.00) MAPTKMT2AALOX15ALDH1A1MEN1
Hydroquinone SCHEMBL15516 0.71
SCHEMBL9432925 0.69 LMNA (0.50) KMT2AMEN1LMNAMGLLTDP1
SCHEMBL19315059 0.67 KMT2A (0.56) MAPTKMT2AALOX15ALDH1A1MEN1
SCHEMBL7041242 0.67 MAPT (0.68) MAPTKMT2AALDH1A1MEN1KDM4E
Hydroquinone SCHEMBL8353108 0.67 ALOX15 (0.89) MAPTKMT2AALOX15ALDH1A1MEN1
Hydroquinone SCHEMBL11552027 0.67
Hydroquinone SCHEMBL7116773 0.67 ALOX15 (0.89) MAPTKMT2AALOX15ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5459266-A Hydroxyphenyl-substituted as monomers for polyesters, polyaryl ates, polyether ketones, polycarbonates, polyepoxides HOECHST CELANESE CORPORATION (US) 1995-10-17 US disclosed
US-5430123-A Polymer compositions containing substituted pyrazines HOECHST CELANESE CORPORATION (US) 1995-07-04 US disclosed
US-5393860-A Functional monomers for high performance polymers HOECHST CELANESE CORPORATION (US) 1995-02-28 US disclosed