Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152788 | 0.95 | RAB9A (0.53) | RAB9ASMN1; SMN2MAPTNPC1STAT3 | |
| SCHEMBL9154167 | 0.95 | RAB9A (0.49) | RAB9ASMN1; SMN2MAPTNPC1STAT3 | |
| SCHEMBL9154233 | 0.93 | MAPT (0.51) | RAB9ASMN1; SMN2MAPTNPC1STAT3 | |
| SCHEMBL9766704 | 0.92 | RAB9A (0.50) | RAB9ASMN1; SMN2MAPTNPC1STAT3 | |
| SCHEMBL9159149 | 0.92 | MAPT (0.53) | RAB9ASMN1; SMN2MAPTNPC1STAT3 | |
| SCHEMBL9155593 | 0.92 | MAPT (0.53) | RAB9ASMN1; SMN2MAPTNPC1STAT3 | |
| SCHEMBL10721748 | 0.92 | RAB9A (0.51) | RAB9ASMN1; SMN2MAPTNPC1STAT3 | |
| SCHEMBL9153776 | 0.90 | MAPT (0.55) | RAB9ASMN1; SMN2MAPTNPC1STAT3 | |
| SCHEMBL9157460 | 0.90 | MAPT (0.55) | RAB9ASMN1; SMN2MAPTNPC1STAT3 | |
| SCHEMBL9161133 | 0.90 | MAPT (0.55) | RAB9ASMN1; SMN2MAPTNPC1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-B1 | PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5205962-A | Stable liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-27 | — | — | US | disclosed |
| EP-0445248-A1 | PYRIDINE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |