SCHEMBL154356

SCHEMBL154356

O=c1ccn([C@@H]2O[C@H](C(O)Br)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.60
SLC28A2 O43868 1/20 0.60
SLC29A1 Q99808 1/20 0.60
SLC28A3 Q9HAS3 1/20 0.60
P2RY2 P41231 12/20 0.53
P2RY6 Q15077 9/20 0.50
P2RY4 P51582 4/20 0.49
P2RY14 Q15391 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5846581 0.89 SLC28A1 (0.63) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL5052768 0.88 SLC28A1 (0.50) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL1696779 0.88 SLC28A1 (0.61) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL4950152 0.88 SLC28A1 (0.61) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL23710653 0.86 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL1585708 0.86 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL566228 0.86 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL16629728 0.86 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL21275617 0.86 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL4280246 0.86 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260097120-A1 INDUCTION OF STEM-LIKE ACTIVATED T CELLS PHIO PHARMACEUTICALS CORP. (US) 2026-04-09 US disclosed
US-12544344-B2 Topical delivery of nucleic acid compounds PHIO PHARMACEUTICALS CORP. (US) 2026-02-10 US disclosed
US-20250302925-A1 CONJUGATED CRISPR-CAS COMPLEXES SYNTHEGO CORPORATION 2025-10-02 US disclosed
US-20250283096-A1 SPHERICAL NUCLEIC ACID-BASED CONSTRUCTS AS IMMUNOSTIMULATORY AGENTS FOR PROPHYLACTIC AND THERAPEUTIC USE FLASHPOINT THERAPEUTICS, INC. (US) 2025-09-11 US disclosed
US-20250171789-A1 ARTIFICIAL NUCLEIC ACID MOLECULES CureVac SE (DE) 2025-05-29 US disclosed
WO-2025101204-A1 INTRATUMORAL TARGETING OF PD-1 PHIO PHARMACEUTICALS CORP. (US) 2025-05-15 WO disclosed
US-20250099628-A1 COMPOSITION AND METHODS FOR IMAGING CELLS UNIV CASE WESTERN RESERVE (US) 2025-03-27 US disclosed
US-12258567-B2 Artificial nucleic acid molecules CureVac SE (DE) 2025-03-25 US disclosed
US-20250020645-A1 A4B1 BINDING APTAMERS UNIVERSITY OF WASHINGTON (US) 2025-01-16 US disclosed
WO-2024182745-A9 COMPOSITIONS FOR TARGETING EXTRACELLULAR VESICLE TRAFFICKING AND METHODS THEREOF THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) 2025-01-16 WO disclosed
WO-2003106640-A2 CELL TARGETING METHODS AND COMPOSITIONS CASE WESTERN RESERVE UNIVERSITY (US) 2003-12-24 WO disclosed
US-20030054408-A1 Methods and systems for identifying proteins RAVI RAMAMOORTHI (US) 2003-03-20 US disclosed
WO-2002086081-A2 METHODS AND SYSTEMS FOR IDENTIFYING PROTEINS CARNEGIE MELLON UNIVERSITY (US) 2002-10-31 WO disclosed
US-6090932-A Method of preparation of known and novel 2'-modified nucleosides by intramolecular nucleophilic displacement PROLIGO LLC (US) 2000-07-18 US disclosed
US-6066484-A ENZYME WHICH DECOMPOSES NUCLEOSIDES TO FREE BASES AND RIBOSE; FOR REDUCING PURINE LEVELS OF FOODS, INCLUDING BEER, TO PREVENT GOUT AND HYPERURICEMIA SUNTORY LIMITED (JP) 2000-05-23 US disclosed
EP-0828855-B1 Oligonucleotide sizing using cleavable primers STANFORD RES INST INT (US) 1999-12-15 EP disclosed
US-5830655-A DETERMINATION THE SIZE OF PRIMER EXTENSION SRI INTERNATIONAL (US) 1998-11-03 US disclosed
EP-0828855-A1 OLIGONUCLEOTIDE SIZING USING CLEAVABLE PRIMERS SRI INTERNATIONAL (US) 1998-03-18 EP disclosed
EP-0825261-A2 Purine nucleosidase from Ochrobactrum anthropi SUNTORY LIMITED (JP) 1998-02-25 EP disclosed
WO-1996037630-A1 OLIGONUCLEOTIDE SIZING USING CLEAVABLE PRIMERS SRI INTERNATIONAL (US) 1996-11-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097120-A1 INDUCTION OF STEM-LIKE ACTIVATED T CELLS CD274, PDCD1LG2, ICOS SLC28A1 1610/4885SLC28A2 1716/4885SLC29A1 878/4885
US-20250099628-A1 COMPOSITION AND METHODS FOR IMAGING CELLS MCL1, TP53, HNRNPAB SLC28A1 3715/4885SLC28A2 3574/4885SLC29A1 3310/4885
US-12544344-B2 Topical delivery of nucleic acid compounds METTL16, NSUN2, RNMT SLC28A1 437/4885SLC28A2 533/4885SLC29A1 165/4885
US-20250302925-A1 CONJUGATED CRISPR-CAS COMPLEXES DCLRE1B, MRE11, FEN1 SLC28A1 3946/4885SLC28A2 4060/4885SLC29A1 3604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.