Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10587136 | 0.84 | MAPT (0.46) | KDM4EDDAH1ALDH1A1LMNAMAPT | |
| SCHEMBL11570093 | 0.83 | ALDH1A1 (0.42) | KDM4EDDAH1ALDH1A1LMNAMAPT | |
| SCHEMBL11130293 | 0.82 | KDM4E (0.39) | KDM4EDDAH1ALDH1A1LMNAMAPT | |
| SCHEMBL225596 | 0.80 | MAPT (0.40) | KDM4EDDAH1ALDH1A1LMNAMAPT | |
| SCHEMBL11499708 | 0.79 | GPR84 (0.40) | KDM4EDDAH1ALDH1A1LMNAMAPT | |
| SCHEMBL6554420 | 0.74 | HTT (0.43) | KDM4EDDAH1ALDH1A1LMNAMAPT | |
| SCHEMBL16916950 | 0.72 | ALDH1A1 (0.41) | KDM4EDDAH1ALDH1A1LMNAMAPT | |
| SCHEMBL11499817 | 0.70 | KDM4E (0.39) | KDM4EDDAH1ALDH1A1LMNAMAPT | |
| SCHEMBL725796 | 0.70 | ALDH1A1 (0.48) | KDM4EDDAH1ALDH1A1LMNAMAPT | |
| SCHEMBL11287716 | 0.69 | DAO (0.39) | KDM4EDDAH1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0688321-A1 | N-(BETA-BRANCHED ALKYL)-1,2-BENZISOTHIAZOLIN-3-ONES, THEIR PREPARATION AND USE AS INDUSTRIAL BIOCIDES | ZENECA LTD (GB) | 1995-12-27 | — | — | EP | claimed |
| WO-1994020479-A1 | N-(BETA-BRANCHED ALKYL)-1,2-BENZISOTHIAZOLIN-3-ONES, THEIR PREPARATION AND USE AS INDUSTRIAL BIOCIDES | ZENECA LIMITED (GB) | 1994-09-15 | — | — | WO | claimed |