Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10925300 | 0.82 | PAK1 (0.61) | PAK1 | |
| SCHEMBL10927535 | 0.82 | PAK1 (0.61) | PAK1 | |
| SCHEMBL8826229 | 0.82 | PAK1 (0.61) | PAK1 | |
| SCHEMBL9160663 | 0.82 | — | — | |
| SCHEMBL1725582 | 0.80 | PAK1 (0.62) | PAK1 | |
| SCHEMBL9159560 | 0.80 | PAK1 (0.41) | PAK1 | |
| SCHEMBL14185050 | 0.73 | SLC6A5 (0.58) | PAK1 | |
| SCHEMBL14185048 | 0.72 | SLC6A5 (0.44) | PAK1 | |
| SCHEMBL6747960 | 0.72 | SLC6A5 (0.44) | PAK1 | |
| SCHEMBL14185049 | 0.72 | SLC6A5 (0.44) | PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478830-A | Pyrazolo pyrimidines; inhibitors of acyl-coenzyme A and cholesterol acyltransferase; antihypercholesterolemic agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-12-26 | — | — | US | disclosed |