Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5568529 | 0.82 | SMN1; SMN2 (0.42) | PTAFRSMN1; SMN2GAACA12CA1 | |
| SCHEMBL7847500 | 0.82 | SMN1; SMN2 (0.45) | PTAFRSMN1; SMN2ALDH1A1TUBB4ATUBB | |
| SCHEMBL6944366 | 0.80 | HTR1A (0.38) | PTAFRSMN1; SMN2MAPTRAB9AL3MBTL1 | |
| SCHEMBL7844096 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2 | |
| SCHEMBL7835713 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2 | |
| SCHEMBL9782164 | 0.72 | MAPT (0.43) | SMN1; SMN2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL6627059 | 0.70 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1HTTLMNAMAPT | |
| SCHEMBL7844847 | 0.70 | SMN1; SMN2 (0.46) | SMN1; SMN2 | |
| SCHEMBL10448821 | 0.69 | PTAFR (0.57) | PTAFRSMN1; SMN2ALDH1A1TUBB4ATUBB | |
| SCHEMBL10448547 | 0.68 | PTAFR (0.58) | PTAFRSMN1; SMN2ALDH1A1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447942-A | Treatment of bronchoconstriction | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1995-09-05 | — | — | US | disclosed |