Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 10/20 | 0.42 |
| ▸ | PPARD | Q03181 | 6/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156745 | 0.89 | TSHR (0.48) | NPC1HPGDTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9167908 | 0.87 | LTA4H (0.51) | NPC1HPGDTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9165782 | 0.82 | PPARA (0.50) | NPC1HPGDTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9158453 | 0.79 | PPARA (0.59) | NPC1HPGDTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9162187 | 0.78 | NPC1 (0.39) | NPC1HPGDTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9163686 | 0.77 | RAB9A (0.46) | NPC1HPGDRAB9ASMN1; SMN2PPARA | |
| SCHEMBL9165311 | 0.76 | PPARA (0.52) | NPC1HPGDTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9163526 | 0.76 | LTA4H (0.48) | NPC1RAB9ASMN1; SMN2ATMPPARA | |
| SCHEMBL9163338 | 0.75 | LTA4H (0.50) | NPC1HPGDTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9157407 | 0.75 | LTA4H (0.47) | NPC1RAB9ASMN1; SMN2ATMPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460472-B1 | Carbamic acid derivatives, their production and use | SUMITOMO CHEMICAL CO (JP) | 1995-03-08 | — | — | EP | claimed |