Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 5/20 | 0.35 |
| ▸ | RARB | P10826 | 5/20 | 0.35 |
| ▸ | RARG | P13631 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | GOT1 | P17174 | 1/20 | 0.35 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | MDH1 | P40925 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9077434 | 0.87 | KDM4E (0.34) | MEN1KMT2ATHRBRECQLNR2E1 | |
| Hydrochloric Acid SCHEMBL9130755 | 0.86 | RARA (0.33) | MEN1KMT2ARARARARBRARG | |
| SCHEMBL8765802 | 0.83 | RARG (0.48) | RECQLRARARARBRARGLMNA | |
| SCHEMBL8765826 | 0.83 | RARG (0.48) | RECQLRARARARBRARGLMNA | |
| SCHEMBL7687187 | 0.83 | NPC1 (0.36) | EPHX2CNR2 | |
| SCHEMBL9453212 | 0.82 | MEN1 (0.47) | MEN1KMT2ALMNAEPHX2ALDH1A1 | |
| SCHEMBL8766160 | 0.79 | RARA (0.46) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL8766140 | 0.79 | RARA (0.46) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL9132556 | 0.79 | SERPINE1 (0.36) | MEN1KMT2ARARARARBRARG | |
| SCHEMBL3681934 | 0.79 | RARB (0.49) | MEN1KMT2ATHRBRECQLNR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409728-B1 | Bi-aromatic esters, process for their preparation and their use in human or animal medicine and in cosmetics | CIRD GALDERMA (FR) | 1995-03-01 | — | — | EP | disclosed |
| EP-0409728-A2 | Bi-aromatic esters, process for their preparation and their use in human or animal medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1991-01-23 | — | — | EP | disclosed |