Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 18/20 | 0.48 |
| ▸ | RARB | P10826 | 17/20 | 0.48 |
| ▸ | RARA | P10276 | 15/20 | 0.48 |
| ▸ | RXRA | P19793 | 7/20 | 0.38 |
| ▸ | RXRB | P28702 | 3/20 | 0.38 |
| ▸ | RXRG | P48443 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765826 | 1.00 | RARG (0.48) | RARGRARBRARARXRARXRB | |
| SCHEMBL9079123 | 0.92 | RARB (0.42) | RARGRARBRARARXRARXRB | |
| SCHEMBL9079111 | 0.92 | RARB (0.42) | RARGRARBRARARXRARXRB | |
| SCHEMBL9077434 | 0.87 | KDM4E (0.34) | RARGRARBRARAKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL9130755 | 0.86 | RARA (0.33) | RARGRARBRARAKDM4ENPC1 | |
| SCHEMBL9158243 | 0.83 | MEN1 (0.36) | RARGRARBRARAKDM4EALDH1A1 | |
| SCHEMBL8766160 | 0.83 | RARA (0.46) | RARGRARBRARALMNATP53 | |
| SCHEMBL8766140 | 0.83 | RARA (0.46) | RARGRARBRARALMNATP53 | |
| SCHEMBL7687187 | 0.83 | NPC1 (0.36) | NPC1 | |
| SCHEMBL8766203 | 0.82 | RARB (0.48) | RARGRARBRARARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584191-B1 | NOVEL AROMATIC AND POLYCYCLIC COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | CIRD GALDERMA (FR) | 1997-08-13 | — | — | EP | disclosed |
| WO-1992019583-A1 | NOVEL AROMATIC AND POLYCYCLIC COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDECINE AND IN COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1992-11-12 | — | — | WO | disclosed |