Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | PPIB | P23284 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9161964 | 0.96 | KMT2A (0.48) | MEN1KMT2ATHRBPKMNPC1 | |
| SCHEMBL9152533 | 0.95 | NPC1 (0.50) | MEN1KMT2ATHRBPKMNPC1 | |
| SCHEMBL9160125 | 0.93 | KMT2A (0.47) | MEN1KMT2ATHRBPKMNPC1 | |
| SCHEMBL9153700 | 0.92 | ALDH1A1 (0.44) | MEN1KMT2ATHRBPKMNPC1 | |
| SCHEMBL9159125 | 0.92 | ALDH1A1 (0.51) | MEN1KMT2ATHRBPKMNPC1 | |
| SCHEMBL9153540 | 0.90 | NPC1 (0.54) | MEN1KMT2ATHRBPKMKCNK3 | |
| SCHEMBL9152283 | 0.88 | MEN1 (0.42) | MEN1KMT2ATHRBPKMNPC1 | |
| SCHEMBL9134216 | 0.88 | MEN1 (0.43) | MEN1KMT2ATHRBPKMKCNK3 | |
| SCHEMBL9159137 | 0.88 | KMT2A (0.43) | MEN1KMT2ATHRBPKMKCNK3 | |
| SCHEMBL9157309 | 0.88 | MEN1 (0.46) | MEN1KMT2ATHRBPKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |