Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160125 | 0.93 | KMT2A (0.47) | KMT2AMEN1THRBPKMNPC1 | |
| SCHEMBL9153700 | 0.92 | ALDH1A1 (0.44) | KMT2AMEN1THRBPKMNPC1 | |
| SCHEMBL9161964 | 0.92 | KMT2A (0.48) | KMT2AMEN1THRBPKMNPC1 | |
| SCHEMBL9152283 | 0.90 | MEN1 (0.42) | KMT2AMEN1THRBPKMNPC1 | |
| SCHEMBL9152533 | 0.89 | NPC1 (0.50) | KMT2AMEN1THRBPKMNPC1 | |
| SCHEMBL9158064 | 0.89 | MEN1 (0.41) | KMT2AMEN1THRBPKMNPC1 | |
| SCHEMBL9158341 | 0.89 | MEN1 (0.41) | KMT2AMEN1THRBPKMNPC1 | |
| SCHEMBL9157309 | 0.88 | MEN1 (0.46) | KMT2AMEN1THRBPKMNPC1 | |
| SCHEMBL9158259 | 0.88 | MEN1 (0.45) | KMT2AMEN1THRBPKMNPC1 | |
| SCHEMBL9153478 | 0.87 | MEN1 (0.43) | KMT2AMEN1THRBPKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |