Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157826 | 0.95 | ALDH1A1 (0.51) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL9157942 | 0.94 | ALDH1A1 (0.50) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL9154966 | 0.90 | ALDH1A1 (0.56) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL4045859 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL29770446 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL9156334 | 0.83 | ALDH1A1 (0.66) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL4665252 | 0.83 | CTSV (0.58) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL9154974 | 0.81 | ALDH1A1 (0.64) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL9155520 | 0.80 | EGFR (0.55) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL9766051 | 0.80 | ALDH1A1 (0.62) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457099-A | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0577325-A1 | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1994-01-05 | — | — | EP | disclosed |