Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1853644 | 0.73 | PIK3CD (0.83) | PIK3CDPIK3CAPIK3CBPIK3CGSMN1; SMN2 | |
| SCHEMBL4850658 | 0.72 | PIK3CD (0.61) | PIK3CDPIK3CAPIK3CBPIK3CGSMN1; SMN2 | |
| SCHEMBL303137 | 0.71 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CBPIK3CGSMN1; SMN2 | |
| SCHEMBL28253992 | 0.71 | SMN1; SMN2 (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGSMN1; SMN2 | |
| SCHEMBL1853490 | 0.70 | HTT (0.64) | PIK3CDPIK3CAPIK3CBPIK3CGSMN1; SMN2 | |
| SCHEMBL25932800 | 0.70 | ALDH1A1 (0.71) | PIK3CDPIK3CAPIK3CBPIK3CGSMN1; SMN2 | |
| SCHEMBL28317825 | 0.70 | AR (0.51) | PIK3CDPIK3CAPIK3CBPIK3CGSMN1; SMN2 | |
| SCHEMBL2559774 | 0.70 | ALDH1A1 (0.58) | PIK3CDPIK3CAPIK3CBPIK3CGSMN1; SMN2 | |
| SCHEMBL31082099 | 0.69 | PIK3CD (0.58) | PIK3CDPIK3CAPIK3CBPIK3CGSMN1; SMN2 | |
| SCHEMBL9963514 | 0.69 | RAB9A (0.74) | SMN1; SMN2RAB9ANPC1ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486041-B1 | A method for producing thiadiazine compounds | AGENCY IND SCIENCE TECHN (JP) | 1995-02-22 | — | — | EP | disclosed |
| US-5138053-A | METHOD FOR PRODUCING THIADIAZINE COMPOUNDS | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0486041-A1 | A method for producing thiadiazine compounds | DIRECTOR-GENERAL OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1992-05-20 | — | — | EP | disclosed |