Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EEF2K | O00418 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14853306 | 0.80 | HSP90AA1 (0.46) | PTPN1PTGS2ALOX5MEN1GAA | |
| SCHEMBL9164941 | 0.77 | ERBB2 (0.33) | EGFRERBB2TNFRSF1A | |
| SCHEMBL8306587 | 0.77 | PTGS2 (0.69) | EGFRERBB2IGF1RPTGS1PTGS2 | |
| SCHEMBL8306585 | 0.77 | PTGS2 (0.69) | EGFRERBB2IGF1RPTGS1PTGS2 | |
| SCHEMBL13045201 | 0.77 | CYP1A2 (0.43) | EGFRERBB2IGF1RPTPN1PTGS1 | |
| SCHEMBL85764 | 0.74 | GABBR2 (0.66) | EGFRGABBR2GABBR1PTGS1PTGS2 | |
| Water SCHEMBL1502204 | 0.72 | GABBR2 (0.63) | EGFRERBB2GABBR2GABBR1PTGS1 | |
| Hydrochloric Acid SCHEMBL31385524 | 0.72 | GABBR2 (0.63) | EGFRGABBR2GABBR1PTGS1PTGS2 | |
| Water SCHEMBL1502206 | 0.72 | GABBR2 (0.63) | EGFRERBB2GABBR2GABBR1PTGS1 | |
| SCHEMBL23801955 | 0.69 | GABBR2 (0.55) | GABBR2GABBR1PTGS1PTGS2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5441984-A | Antidiabetic agent | ELI LILLY AND COMPANY (US) | 1995-08-15 | — | — | US | disclosed |