Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EDNRB | P24530 | 10/20 | 0.43 |
| ▸ | EDNRA | P25101 | 10/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975607 | 0.79 | KDM4E (0.42) | KDM4EALDH1A1EDNRBEDNRACYP1A2 | |
| SCHEMBL9352927 | 0.73 | CYP1A2 (0.38) | KDM4EALDH1A1EDNRBEDNRACYP1A2 | |
| SCHEMBL9159299 | 0.73 | EDNRB (0.41) | KDM4EALDH1A1EDNRBEDNRALMNA | |
| SCHEMBL8975739 | 0.71 | CYP1A2 (0.42) | KDM4EALDH1A1EDNRBEDNRACYP1A2 | |
| SCHEMBL9132905 | 0.69 | ALDH1A1 (0.40) | KDM4EALDH1A1EDNRBEDNRACYP1A2 | |
| SCHEMBL9461243 | 0.68 | KDM4E (0.48) | KDM4EALDH1A1EDNRBEDNRACYP1A2 | |
| SCHEMBL9356618 | 0.68 | ALDH1A1 (0.36) | KDM4EALDH1A1EDNRBEDNRACYP1A2 | |
| SCHEMBL8873001 | 0.67 | ALDH1A1 (0.38) | KDM4EALDH1A1EDNRBEDNRACYP1A2 | |
| SCHEMBL8976238 | 0.67 | ALDH1A1 (0.38) | KDM4EALDH1A1EDNRBEDNRACYP1A2 | |
| SCHEMBL8872731 | 0.67 | ALDH1A1 (0.41) | KDM4EALDH1A1EDNRBEDNRACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5239035-A | — | — | None | — | — | JP | disclosed |
| US-5446013-A | 2-alkyl-or-aryl-substituted-2-(pyrimidinyl-or-traizinyl-oxy(or-thio))-acotic acid derivatives, process for preparation, and use as herbicides or plant-growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-29 | — | — | US | disclosed |
| JP-H05239035-A | PYRIMIDINYL-OR TRIAZINYL-OXY-(OR-THIO)-CARBOXYLIC ACID DERIVATIVE, THOSE PRODUCTION AND USE AS HERBICIDE OR PLANT GROWTH REGULATOR THEREOF | HOECHST AG | 1993-09-17 | — | — | JP | disclosed |