SCHEMBL8975607

SCHEMBL8975607

COc1cc(OC)nc(C(F)(C(=O)O)C(C)C)n1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.40
LMNA P02545 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
EDNRB P24530 9/20 0.39
EDNRA P25101 9/20 0.39
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8975739 0.86 CYP1A2 (0.42) KDM4EALDH1A1CYP1A2LMNATDP1
SCHEMBL8976238 0.81 ALDH1A1 (0.38) KDM4EALDH1A1CYP1A2LMNAEDNRB
SCHEMBL9159449 0.79 KDM4E (0.43) KDM4EALDH1A1CYP1A2LMNATDP1
SCHEMBL26685120 0.74 CHRNA4 (0.34) KDM4EALDH1A1LMNATDP1
SCHEMBL8975656 0.72 EDNRB (0.49) KDM4EALDH1A1EDNRBEDNRA
SCHEMBL17542095 0.69 TDP1 (0.60) KDM4EALDH1A1CYP1A2LMNATDP1
SCHEMBL9352927 0.69 CYP1A2 (0.38) KDM4EALDH1A1CYP1A2LMNATDP1
SCHEMBL6826490 0.68 LMNA (0.35) CYP1A2LMNAEDNRBEDNRASMN1; SMN2
SCHEMBL9132905 0.68 ALDH1A1 (0.40) KDM4EALDH1A1CYP1A2LMNAEDNRB
SCHEMBL9461243 0.67 KDM4E (0.48) KDM4EALDH1A1CYP1A2LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5502028-A Herbicidal pyrimidinyl or triazinyl haloacetic acid derivatives SCHERING AGROCHEMICALS LIMITED (GB) 1996-03-26 US disclosed