Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18644116 | 0.78 | PSMB5 (0.55) | PSMB5ALDH1A1NPSR1HTTHPGD | |
| SCHEMBL5767153 | 0.77 | GPR35 (0.46) | ALDH1A1NPSR1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL20799500 | 0.77 | PSMB5 (0.50) | PSMB5ALDH1A1NPSR1HTTHPGD | |
| SCHEMBL9167511 | 0.76 | CRHBP (0.44) | MAPTMEN1KMT2A | |
| SCHEMBL9164726 | 0.76 | KMT2A (0.41) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL9159351 | 0.76 | PSMB5 (0.49) | PSMB5ALDH1A1NPSR1HTTHPGD | |
| SCHEMBL9161086 | 0.75 | MEN1 (0.39) | ALDH1A1HTTMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9164365 | 0.75 | MAPT (0.47) | ALDH1A1NPSR1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL9159546 | 0.75 | DHODH (0.40) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15215125 | 0.75 | TSHR (0.44) | ALDH1A1NPSR1MAPTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1028754-C | process for preparing quinoline derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-06-07 | — | — | CN | disclosed |
| EP-0354994-B1 | Quinoline derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5254565-A | Enzyme inhibitors; anticholesterol agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-19 | — | — | US | disclosed |
| EP-0354994-A2 | Quinoline derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-02-21 | — | — | EP | disclosed |
| CN-1039416-A | Quinoline and preparation thereof and purposes | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1990-02-07 | — | — | CN | disclosed |