Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31202591 | 0.92 | TDP1 (0.51) | THRBTDP1ALDH1A1POLBAPEX1 | |
| SCHEMBL42893 | 0.92 | HCAR2 (0.51) | THRBTDP1ALDH1A1POLBAPEX1 | |
| SCHEMBL7565572 | 0.92 | THRB (0.59) | THRBTDP1ALDH1A1POLBAPEX1 | |
| SCHEMBL554380 | 0.91 | THRB (0.51) | THRBTDP1ALDH1A1POLBAPEX1 | |
| Methane SCHEMBL4468486 | 0.90 | HCAR2 (0.50) | THRBTDP1ALDH1A1POLBAPEX1 | |
| SCHEMBL488918 | 0.89 | THRB (0.53) | THRBTDP1ALDH1A1POLBAPEX1 | |
| SCHEMBL27973892 | 0.89 | HCAR2 (0.49) | THRBTDP1ALDH1A1POLBAPEX1 | |
| Methacrylic Acid SCHEMBL8131805 | 0.89 | HCAR2 (0.49) | THRBTDP1ALDH1A1POLBAPEX1 | |
| Ethylene Glycol SCHEMBL6490846 | 0.87 | HCAR2 (0.47) | THRBTDP1ALDH1A1POLBAPEX1 | |
| SCHEMBL316845 | 0.87 | THRB (0.54) | THRBTDP1ALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5473032-A | Includes acrylic copolymer having hydroxyl groups | HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-12-05 | — | — | US | disclosed |