Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42893 | 0.98 | HCAR2 (0.51) | HCAR2ESR1ESR2TDP1THRB | |
| SCHEMBL27973892 | 0.95 | HCAR2 (0.49) | HCAR2ESR1ESR2TDP1THRB | |
| Methacrylic Acid SCHEMBL8131805 | 0.95 | HCAR2 (0.49) | HCAR2ESR1ESR2TDP1THRB | |
| Ethylene Glycol SCHEMBL6490846 | 0.93 | HCAR2 (0.47) | HCAR2ESR1ESR2TDP1THRB | |
| SCHEMBL7937982 | 0.92 | HCAR2 (0.46) | HCAR2ESR1ESR2TDP1THRB | |
| SCHEMBL150510 | 0.92 | LMNA (0.49) | HCAR2ESR1ESR2TDP1THRB | |
| Acrylic Acid SCHEMBL3925457 | 0.91 | HCAR2 (0.53) | HCAR2ESR1ESR2TDP1THRB | |
| SCHEMBL28186333 | 0.91 | APP (0.46) | HCAR2ESR1ESR2TDP1THRB | |
| SCHEMBL9159591 | 0.90 | THRB (0.54) | HCAR2ESR1ESR2TDP1THRB | |
| SCHEMBL9739790 | 0.89 | ELANE (0.54) | HCAR2ESR1ESR2TDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049923-A2 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | Advanced Vision Science, Inc. (US) | 2009-04-22 | — | — | EP | claimed |
| WO-2008013950-A2 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | ADVANCED VISION SCIENCE, INC. (US) | 2008-01-31 | — | — | WO | claimed |