SCHEMBL9159989

SCHEMBL9159989

CC1=NC(=O)CN1c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
MAPT P10636 3/20 0.42
KDM4E B2RXH2 2/20 0.42
GAA P10253 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP1A2 P05177 1/20 0.41
CHRM2 P08172 1/20 0.41
CYP3A4 P08684 1/20 0.41
CHRM1 P11229 1/20 0.41
PTGS1 P23219 1/20 0.41
DRD3 P35462 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CTSG P08311 4/20 0.40
CMA1 P23946 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11604852 0.78 SIGMAR1 (0.58) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL11601832 0.77 NPC1 (0.41) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL10849930 0.75 MYC (0.49) MEN1KMT2AMAPTKDM4EGAA
SCHEMBL10620662 0.74 SIGMAR1 (0.67) NPC1RAB9AMEN1KMT2AMAPT
Formaldehyde SCHEMBL28819216 0.74 SIGMAR1 (0.61) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL1610854 0.72 NPC1 (0.48) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL9379824 0.70 HPGD (0.47) MEN1KMT2AMAPTKDM4EGAA
SCHEMBL9834330 0.69 KMT2A (0.61) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL7745621 0.69 KMT2A (0.45) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL6853577 0.69 GAA (0.50) NPC1RAB9AMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0363104-B1 Silver halide photographic material EASTMAN KODAK CO (US) 1995-03-22 EP disclosed
US-5079139-A Red sensitive, but not green sensitive, graphic arts materials for exposure to helium neon laser EASTMAN KODAK COMPANY (US) 1992-01-07 US disclosed
EP-0363104-A2 Silver halide photographic material EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-04-11 EP disclosed