Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6856024 | 0.81 | DDB1 (0.47) | GAAKDM4EMAPTTDP1NPC1 | |
| SCHEMBL1610854 | 0.80 | NPC1 (0.48) | GAAKDM4EMAPTTDP1NPC1 | |
| SCHEMBL11604852 | 0.71 | SIGMAR1 (0.58) | GAAKDM4EMAPTTDP1NPC1 | |
| SCHEMBL9834330 | 0.69 | KMT2A (0.61) | GAAKDM4EMAPTTDP1NPC1 | |
| SCHEMBL9159989 | 0.69 | NPC1 (0.45) | GAAKDM4EMAPTTDP1NPC1 | |
| SCHEMBL7745621 | 0.69 | KMT2A (0.45) | GAAKDM4EMAPTTDP1NPC1 | |
| SCHEMBL6858115 | 0.69 | KMT2A (0.44) | KMT2AMEN1LMNASMN1; SMN2DDB1 | |
| SCHEMBL1685398 | 0.67 | KMT2A (0.56) | GAAKDM4EMAPTTDP1NPC1 | |
| SCHEMBL11601832 | 0.66 | NPC1 (0.41) | GAAKDM4EMAPTTDP1NPC1 | |
| SCHEMBL7941727 | 0.65 | MAPT (0.58) | GAAKDM4EMAPTTDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6784293-B1 | SOLUTION AND SOLID-PHASE SYNTHESIS OF BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/ DIHYDROTHIOURACILS | THE PROCTER & GAMBLE COMPANY | 2004-08-31 | — | — | US | disclosed |