Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.46 |
| ▸ | GLRB | P48167 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | PEPD | P12955 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPN | P05981 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2276660 | 0.82 | GAA (1.00) | GAAALDH1A1TDP1CA2CA1 | |
| SCHEMBL295404 | 0.82 | ALDH1A1 (0.72) | GAAALDH1A1TDP1CA2CA1 | |
| SCHEMBL29163030 | 0.82 | GAA (0.62) | GAAALDH1A1TDP1CA2CA1 | |
| SCHEMBL9377717 | 0.81 | GAA (0.66) | GAAALDH1A1TDP1CA2CA1 | |
| SCHEMBL9648938 | 0.81 | ALDH1A1 (0.59) | GAAALDH1A1TDP1CA2CA1 | |
| SCHEMBL8335780 | 0.80 | GAA (0.64) | GAAALDH1A1TDP1CA2CA1 | |
| SCHEMBL9812317 | 0.79 | GAA (0.68) | GAAALDH1A1TDP1CA2CA1 | |
| SCHEMBL3483031 | 0.78 | GAA (0.66) | GAAALDH1A1TDP1CA2CA1 | |
| SCHEMBL9807633 | 0.77 | GAA (0.69) | GAAALDH1A1TDP1CA2CA1 | |
| SCHEMBL10747935 | 0.77 | ALDH1A1 (0.64) | GAAALDH1A1TDP1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5441984-A | Antidiabetic agent | ELI LILLY AND COMPANY (US) | 1995-08-15 | — | — | US | disclosed |
| CN-1028754-C | process for preparing quinoline derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-06-07 | — | — | CN | disclosed |