Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165808 | 0.87 | PPARG (0.66) | PPARG | |
| SCHEMBL9165519 | 0.87 | PPARG (0.49) | PPARG | |
| SCHEMBL477 | 0.83 | AGTR1 (0.55) | — | |
| SCHEMBL8395737 | 0.81 | PPARG (0.75) | PPARG | |
| SCHEMBL732 | 0.81 | PPARG (0.51) | PPARG | |
| SCHEMBL7299126 | 0.81 | AGTR1 (0.59) | PPARG | |
| SCHEMBL7310213 | 0.80 | PPARG (0.56) | PPARG | |
| SCHEMBL7914065 | 0.80 | AGTR1 (0.53) | — | |
| SCHEMBL7905325 | 0.79 | AGTR1 (0.58) | PPARG | |
| SCHEMBL8944686 | 0.79 | PPARG (0.76) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389660-A | Hypotensive agents | MERCK & CO., INC. (US) | 1995-02-14 | — | — | US | disclosed |
| US-5164407-A | Hypotensive agents | MERCK & CO., INC. (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0407102-A1 | Substituted imidazo-fused 5-membered ring heterocycles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1991-01-09 | — | — | EP | disclosed |