Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160198 | 1.00 | ESR1 (0.47) | ESR1SLC6A2SLC6A4SLC6A3ACP3 | |
| SCHEMBL9160194 | 1.00 | ESR1 (0.47) | ESR1SLC6A2SLC6A4SLC6A3ACP3 | |
| SCHEMBL10710482 | 0.85 | ADRA2A (0.36) | ESR1SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL9161755 | 0.80 | CA1 (0.46) | ACHETSHRADRA2BALDH1A1NPSR1 | |
| SCHEMBL18501011 | 0.80 | ESR1 (0.47) | ESR1SLC6A2SLC6A4SLC6A3ACP3 | |
| SCHEMBL9161751 | 0.80 | CA1 (0.46) | ACHETSHRADRA2BALDH1A1NPSR1 | |
| SCHEMBL9161769 | 0.80 | CA1 (0.46) | ACHETSHRADRA2BALDH1A1NPSR1 | |
| SCHEMBL9167590 | 0.79 | ESR1 (0.42) | ESR1SLC6A2SLC6A4SLC6A3ACP3 | |
| SCHEMBL9167586 | 0.79 | ESR1 (0.42) | ESR1SLC6A2SLC6A4SLC6A3ACP3 | |
| SCHEMBL9167579 | 0.79 | ESR1 (0.42) | ESR1SLC6A2SLC6A4SLC6A3ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469887-B1 | Acetamide derivatives | ZENECA LTD (GB) | 1994-12-14 | — | — | EP | claimed |
| US-5270342-A | Acetamide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | claimed |
| US-5430060-A | Aldose reductase inhibitor | ZENECA LIMITED (GB) | 1995-07-04 | — | — | US | disclosed |
| US-5270342-A | Acetamide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | disclosed |