Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | FBP1 | P09467 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637377 | 1.00 | APP (0.78) | APPALDH1A1MAPTPOLBFBP1 | |
| SCHEMBL900894 | 0.92 | ALDH1A1 (0.75) | APPALDH1A1MAPTPOLBFBP1 | |
| SCHEMBL900893 | 0.92 | ALDH1A1 (0.75) | APPALDH1A1MAPTPOLBFBP1 | |
| SCHEMBL7622323 | 0.90 | APP (0.95) | APPMAPTFBP1KMT2AMEN1 | |
| SCHEMBL11121103 | 0.90 | APP (0.95) | APPMAPTFBP1KMT2AMEN1 | |
| SCHEMBL11121099 | 0.90 | APP (0.95) | APPMAPTFBP1KMT2AMEN1 | |
| SCHEMBL7622329 | 0.90 | APP (0.95) | APPMAPTFBP1KMT2AMEN1 | |
| SCHEMBL8926613 | 0.88 | APP (1.00) | APPMAPTFBP1KMT2AMEN1 | |
| SCHEMBL8926611 | 0.88 | APP (1.00) | APPMAPTFBP1KMT2AMEN1 | |
| SCHEMBL9750387 | 0.88 | APP (1.00) | APPMAPTFBP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470692-A | Integrated optic components | AKZO NOBEL N.V. (NL) | 1995-11-28 | — | — | US | claimed |