SCHEMBL900893

SCHEMBL900893

Nc1ccc(/C=C/c2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.75
APP P05067 1/20 0.64
MAPT P10636 4/20 0.63
RAB9A P51151 3/20 0.63
NPC1 O15118 2/20 0.63
FBP1 P09467 1/20 0.62
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
PTGS2 P35354 6/20 0.59
CYP19A1 P11511 4/20 0.59
PTGS1 P23219 2/20 0.59
POLB P06746 1/20 0.55
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
MAPK1 P28482 1/20 0.49
HTT P42858 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
GALK1 P51570 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL900894 1.00 ALDH1A1 (0.75) ALDH1A1APPMAPTRAB9ANPC1
SCHEMBL8637377 0.92 APP (0.78) ALDH1A1APPMAPTRAB9ANPC1
SCHEMBL9160280 0.92 APP (0.78) ALDH1A1APPMAPTRAB9ANPC1
SCHEMBL9170804 0.89 APP (0.78) APPMAPTRAB9ANPC1FBP1
SCHEMBL458177 0.89 APP (0.78) APPMAPTRAB9ANPC1FBP1
SCHEMBL458178 0.89 APP (0.78) APPMAPTRAB9ANPC1FBP1
SCHEMBL14947048 0.89 APP (0.78) APPMAPTRAB9ANPC1FBP1
SCHEMBL9170800 0.89 APP (0.78) APPMAPTRAB9ANPC1FBP1
4-Nitroaniline SCHEMBL13529022 0.87 ALDH1A1 (1.00) ALDH1A1MAPTRAB9AMEN1KMT2A
4-Nitroaniline SCHEMBL16451 0.87 ALDH1A1 (1.00) ALDH1A1MAPTRAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3550030-B1 METHOD FOR MEASURING GLYCATION RATE OF HEMOGLOBIN TOYO BOSEKI (JP) 2025-01-01 EP claimed
CN-112940527-B Asymmetric azo dye and preparation method and application thereof 江苏和成新材料有限公司 2023-02-28 CN claimed
US-5420172-A Cross-linked epoxy resins having non-linear optical properties SIEMENS AKTIENGESELLSCHAFT (DE) 1995-05-30 US claimed
US-5342904-A Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1994-08-30 US claimed
EP-0593866-A1 Crosslinked epoxy resins having nonlinear optical properties SIEMENS AKTIENGESELLSCHAFT (DE) 1994-04-27 EP claimed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US claimed
WO-1991003748-A1 ELECTRO-OPTIC WAVEGUIDE DEVICE HOECHST CELANESE CORPORATION (US) 1991-03-21 WO claimed
EP-0413903-A1 Waveguide electrooptic light modulator with low optical loss HOECHST CELANESE CORPORATION (US) 1991-02-27 EP claimed
US-4936645-A Waveguide electrooptic light modulator with low optical loss HOECHST CELANESE CORP. (US) 1990-06-26 US claimed
JP-6065217-A None JP disclosed
US-11866584-B2 High-refractive-index composition, high-refractive-index film, and method for manufacturing high-refractive-index film LG CHEM, LTD. (KR) 2024-01-09 US disclosed
CN-112940527-B Asymmetric azo dye and preparation method and application thereof 江苏和成新材料有限公司 2023-02-28 CN disclosed
US-11382991-B2 Molecular probes for imaging of myelin CASE WESTERN RESERVE UNIVERSITY (US) 2022-07-12 US disclosed
CN-111801388-B High refractive composition, high refractive film, and method for manufacturing high refractive film 株式会社LG化学 2022-04-01 CN disclosed
US-4898691-A Organic nonlinear optical media HOECHST CELANESE CORPORATION (US) 1990-02-06 US disclosed
US-4898691-A Organic nonlinear optical media HOECHST CELANESE CORPORATION (US) 1990-02-06 US disclosed
US-4892682-A Azomethine compositions having nonlinear optical properties HOECHST CELANESE CORPORATION (US) 1990-01-09 US disclosed
EP-0322708-A2 Polymers with amide groups in the side chains F. HOFFMANN-LA ROCHE AG (CH) 1989-07-05 EP disclosed
EP-0150676-B1 1:2 CHROMIUM COMPLEX DYES CIBA-GEIGY AG (CH) 1988-10-12 EP disclosed
EP-0150676-A2 1:2 Chromium complex dyes CIBA-GEIGY AG (CH) 1985-08-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11382991-B2 Molecular probes for imaging of myelin MAG, MYT1, PMP22 ALDH1A1 3088/4885APP 2179/4885MAPT 676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.