Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160629 | 0.85 | MTNR1A (0.48) | MTNR1AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9440359 | 0.76 | MTNR1A (0.48) | MTNR1AKDM4C | |
| SCHEMBL9160485 | 0.75 | MGAM (0.42) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL9160573 | 0.74 | MTNR1A (0.56) | MTNR1AMAPTKDM4C | |
| SCHEMBL27312668 | 0.74 | MTNR1A (0.52) | MTNR1AMGAMAMY1AGAASI | |
| SCHEMBL8481573 | 0.73 | MTNR1A (0.66) | MTNR1AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL23891754 | 0.73 | MTNR1A (0.48) | MTNR1AMGAMAMY1AGAASI | |
| SCHEMBL17726680 | 0.72 | MTNR1A (0.55) | MTNR1AMGAMAMY1AGAASI | |
| SCHEMBL11732644 | 0.71 | CYP3A4 (0.56) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11206749 | 0.71 | TDP1 (0.61) | ALDH1A1MEN1KMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5442060-A | Treating hyperlipemia, atherosclerosis | MITSUBISHI KASEI CORPORATION (JP) | 1995-08-15 | — | — | US | disclosed |
| EP-0591830-A1 | Carboxamide and urea derivatives having ACAT-inhibiting activityM | Mitsubishi Chemical Corporation (JP) | 1994-04-13 | — | — | EP | disclosed |