Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | BID | P55957 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23891754 | 0.93 | MTNR1A (0.48) | MTNR1AEEDKDM4C | |
| SCHEMBL19772837 | 0.86 | MTNR1A (0.45) | MTNR1AEEDKDM4C | |
| SCHEMBL9579476 | 0.81 | MTNR1A (0.46) | MTNR1AEEDKDM4C | |
| SCHEMBL7054345 | 0.81 | LIPG (0.49) | MTNR1ALIPGBIDMCL1BCL2L1 | |
| SCHEMBL18153979 | 0.81 | LIPG (0.49) | MTNR1ALIPGBIDMCL1BCL2L1 | |
| SCHEMBL29432879 | 0.81 | LIPG (0.49) | MTNR1ALIPGBIDMCL1BCL2L1 | |
| SCHEMBL7499810 | 0.79 | MTNR1A (0.44) | MTNR1AEEDKDM4C | |
| SCHEMBL17969064 | 0.79 | MTNR1A (0.48) | MTNR1AEEDKDM4C | |
| SCHEMBL28222763 | 0.79 | LIPG (0.46) | MTNR1ALIPGBIDMCL1BCL2L1 | |
| SCHEMBL9160573 | 0.78 | MTNR1A (0.56) | MTNR1AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439059-B1 | 1-Phenylalkyl-3-phenylurea derivative | MITSUBISHI CHEM IND (JP) | 1994-08-24 | — | — | EP | disclosed |
| US-5202351-A | Treating hyperlipemia, atherosclerosis | MITSUBISHI KASEI CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0439059-A2 | 1-Phenylalkyl-3-phenylurea derivative | Mitsubishi Chemical Corporation (JP) | 1991-07-31 | — | — | EP | disclosed |