Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160639 | 1.00 | PAM (0.40) | PAMALDH1A1CYP2D6ALOX15KMT2A | |
| SCHEMBL8828161 | 0.79 | TBXAS1 (0.39) | PAMALDH1A1CYP2D6KMT2A | |
| SCHEMBL8828171 | 0.79 | TBXAS1 (0.39) | PAMALDH1A1CYP2D6KMT2A | |
| SCHEMBL9158841 | 0.73 | PAM (0.54) | PAMALDH1A1CYP2D6ALOX15KMT2A | |
| SCHEMBL9158830 | 0.73 | PAM (0.54) | PAMALDH1A1CYP2D6ALOX15KMT2A | |
| SCHEMBL10796425 | 0.66 | TBXAS1 (0.51) | PAMALDH1A1KMT2A | |
| SCHEMBL10801704 | 0.65 | PAM (0.47) | PAMALDH1A1 | |
| SCHEMBL10796438 | 0.63 | PAM (0.45) | PAM | |
| SCHEMBL6022622 | 0.63 | KDM4E (0.52) | PAMKMT2A | |
| SCHEMBL6022618 | 0.63 | KDM4E (0.52) | PAMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430059-A | Treating heart disease | EISAI CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| EP-0633248-A1 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0589491-A1 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1994-03-30 | — | — | EP | disclosed |
| US-5292770-A | Butenoic acid derivatives | EISAI CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| US-5166188-A | Cardiovascular disorders, antiischemic agents | EISAI CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0399358-A2 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |