Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160666 | 1.00 | CYP3A4 (0.38) | CYP3A4L3MBTL1CA12CA1CA2 | |
| SCHEMBL9160678 | 1.00 | CYP3A4 (0.38) | CYP3A4L3MBTL1CA12CA1CA2 | |
| SCHEMBL9167579 | 0.81 | ESR1 (0.42) | CYP3A4L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL9167586 | 0.81 | ESR1 (0.42) | CYP3A4L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL9167590 | 0.81 | ESR1 (0.42) | CYP3A4L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL9165953 | 0.80 | KMT2A (0.39) | CYP3A4L3MBTL1IDO1TDO2MEN1 | |
| SCHEMBL9165962 | 0.80 | KMT2A (0.39) | CYP3A4L3MBTL1IDO1TDO2MEN1 | |
| SCHEMBL9165958 | 0.80 | KMT2A (0.39) | CYP3A4L3MBTL1IDO1TDO2MEN1 | |
| SCHEMBL11684215 | 0.79 | SMN1; SMN2 (0.37) | CYP3A4ALDH1A1CES2CES1LMNA | |
| SCHEMBL8022572 | 0.76 | L3MBTL1 (0.43) | CYP3A4L3MBTL1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469887-B1 | Acetamide derivatives | ZENECA LTD (GB) | 1994-12-14 | — | — | EP | claimed |
| US-5270342-A | Acetamide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | claimed |
| US-5430060-A | Aldose reductase inhibitor | ZENECA LIMITED (GB) | 1995-07-04 | — | — | US | disclosed |
| US-5270342-A | Acetamide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | disclosed |