Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9426072 | 0.99 | ALDH1A1 (0.50) | ALDH1A1HTTMEN1KMT2ACYP2C19 | |
| SCHEMBL9154438 | 0.89 | ALDH1A1 (0.51) | ALDH1A1HTTMEN1KMT2ACYP2C19 | |
| SCHEMBL9425893 | 0.89 | ALDH1A1 (0.51) | ALDH1A1HTTMEN1KMT2ACYP2C19 | |
| Hydrochloric Acid SCHEMBL9425757 | 0.89 | ALDH1A1 (0.51) | ALDH1A1HTTMEN1KMT2ACYP2C19 | |
| SCHEMBL9156987 | 0.88 | ALDH1A1 (0.55) | ALDH1A1HTTMEN1KMT2ACYP2C19 | |
| SCHEMBL9426204 | 0.88 | KMT2A (0.47) | ALDH1A1MEN1KMT2ATGM2KDM4E | |
| SCHEMBL9426464 | 0.88 | ALDH1A1 (0.55) | ALDH1A1HTTMEN1KMT2ACYP2C19 | |
| Hydrochloric Acid SCHEMBL9426160 | 0.88 | ALDH1A1 (0.55) | ALDH1A1HTTMEN1KMT2ACYP2C19 | |
| SCHEMBL9426250 | 0.86 | ALDH1A1 (0.53) | ALDH1A1HTTMEN1KMT2ACYP2C19 | |
| SCHEMBL9160835 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HTTMEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533516-B1 | Amides of 1-(alkoxybenzyl)piperazines, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-02-08 | — | — | EP | disclosed |
| US-5340809-A | Antihypoxic, antiischemic agents | ADIR ET COMPAGNIE (FR) | 1994-08-23 | — | — | US | disclosed |
| EP-0533516-A2 | Amides of 1-(alkoxybenzyl)piperazines, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-03-24 | — | — | EP | disclosed |