Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784596 | 0.77 | — | — | |
| SCHEMBL1784598 | 0.77 | — | — | |
| SCHEMBL9009862 | 0.72 | — | — | |
| SCHEMBL789104 | 0.69 | — | — | |
| SCHEMBL789287 | 0.69 | — | — | |
| SCHEMBL789595 | 0.69 | — | — | |
| SCHEMBL8418779 | 0.67 | — | — | |
| SCHEMBL14647818 | 0.67 | — | — | |
| SCHEMBL8053928 | 0.67 | ALDH1A1 (0.31) | — | |
| SCHEMBL19758117 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401732-A | Autoimmune diseases | LEO PHARMACEUTICAL PRODUCTS LTD. A/S KEMISKE FABRIK PRODUKIONSAKTIESE SKAB (DK) | 1995-03-28 | — | — | US | disclosed |
| EP-0460032-B1 | NOVEL VITAMIN D ANALOGUES | LEO PHARM PROD LTD (DK) | 1994-04-27 | — | — | EP | disclosed |
| EP-0460032-A1 | NOVEL VITAMIN D ANALOGUES. | LEO PHARM PROD LTD (DK) | 1991-12-11 | — | — | EP | disclosed |
| WO-1990009991-A1 | NOVEL VITAMIN D ANALOGUES | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1990-09-07 | — | — | WO | disclosed |