Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639475 | 0.80 | ERN1 (0.43) | CYP3A4MAPTMAOBMAPK1LMNA | |
| SCHEMBL10689989 | 0.80 | ACHE (0.43) | CYP3A4MAPTMAOBALOX5PTGS2 | |
| SCHEMBL2164186 | 0.80 | CA12 (0.41) | CYP3A4MAPTMAOBCA1CA2 | |
| SCHEMBL27949662 | 0.80 | CYP3A4 (0.46) | CYP3A4MAPTMAOBALOX5PTGS2 | |
| SCHEMBL3594844 | 0.78 | ERN1 (0.42) | CYP3A4MAPTMAOBALOX5PTGS2 | |
| SCHEMBL4406700 | 0.78 | CYP3A4 (0.45) | CYP3A4MAPTMAOBALOX5PTGS2 | |
| SCHEMBL5658885 | 0.78 | MAPT (0.35) | CYP3A4MAPTMAOBALOX5PTGS2 | |
| SCHEMBL3921146 | 0.77 | TSHR (0.36) | CYP3A4MAPTESR1ESR2TDP1 | |
| SCHEMBL4438220 | 0.75 | LMNA (0.60) | CYP3A4MAPTPTGS2CA1CA2 | |
| SCHEMBL11606239 | 0.75 | TNKS2 (0.40) | CYP3A4ALOX5PTGS2TDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526302-B1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | OREAL (FR) | 1995-03-01 | — | — | EP | claimed |
| EP-0526302-A1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | L'OREAL (FR) | 1993-02-03 | — | — | EP | claimed |
| EP-0526302-B1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | OREAL (FR) | 1995-03-01 | — | — | EP | disclosed |
| EP-0526302-A1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | L'OREAL (FR) | 1993-02-03 | — | — | EP | disclosed |