Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NNMT | P40261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29912736 | 0.87 | RIPK1 (0.69) | RIPK1HTTALDH1A1L3MBTL1P2RX7 | |
| SCHEMBL17882323 | 0.87 | RIPK1 (0.69) | RIPK1HTTALDH1A1L3MBTL1P2RX7 | |
| SCHEMBL4243583 | 0.80 | P2RX7 (0.47) | RIPK1MEN1KMT2AP2RX7EPHX2 | |
| SCHEMBL4032263 | 0.77 | P2RX7 (0.53) | MEN1MAPTKMT2AP2RX7MAOB | |
| SCHEMBL5315312 | 0.77 | P2RX7 (0.52) | RIPK1MEN1KMT2AP2RX7EPHX2 | |
| SCHEMBL9360380 | 0.77 | HTT (0.55) | HTTMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL12791296 | 0.75 | P2RX7 (0.46) | RIPK1MEN1KMT2AP2RX7EPHX2 | |
| SCHEMBL3568253 | 0.75 | P2RX7 (0.53) | MEN1ALDH1A1KMT2AP2RX7EPHX2 | |
| SCHEMBL23482150 | 0.74 | P2RX7 (0.56) | RIPK1MEN1KMT2AP2RX7MAOB | |
| SCHEMBL18887627 | 0.74 | P2RX7 (0.50) | P2RX7BDKRB1MAOBHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401166-B1 | Nitrogen-containing titanocenes and their use | CIBA GEIGY AG (CH) | 1995-02-22 | — | — | EP | disclosed |
| US-5068371-A | Photoinitiators for polymerization | CIBA-GEIGY CORPORATION (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0401166-A2 | Nitrogen-containing titanocenes and their use | CIBA-GEIGY AG (CH) | 1990-12-05 | — | — | EP | disclosed |