Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27335708 | 0.83 | KMT2A (0.44) | ALDH1A1CYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL15286635 | 0.77 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL28340800 | 0.76 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1MAPK1PAMSMN1; SMN2 | |
| SCHEMBL27842393 | 0.75 | PLAU (0.48) | L3MBTL1ALDH1A1CYP1A2CYP2C19TSHR | |
| SCHEMBL14667498 | 0.73 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL1229088 | 0.72 | ALPI (0.53) | — | |
| SCHEMBL28945036 | 0.72 | ALPI (0.53) | — | |
| Benzene SCHEMBL9407299 | 0.72 | ALDH1A1 (0.65) | L3MBTL1ALDH1A1MAPK1PAMSMN1; SMN2 | |
| SCHEMBL248113 | 0.72 | ALDH1A1 (0.65) | L3MBTL1ALDH1A1MAPK1PAMSMN1; SMN2 | |
| SCHEMBL664857 | 0.72 | ALDH1A1 (0.65) | L3MBTL1ALDH1A1MAPK1PAMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385804-A | Silicon containing negative resist for DUV, I-line or E-beam lithography comprising an aromatic azide side group in the polysilsesquioxane polymer | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1995-01-31 | — | — | US | disclosed |