Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | FNTA | P49354 | 1/20 | 0.61 |
| ▸ | FNTB | P49356 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | AHR | P35869 | 1/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | MPO | P05164 | 2/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2874856 | 0.84 | MEN1 (0.58) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL12691322 | 0.81 | MEN1 (0.65) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 | |
| Indole-3-Acetic Acid SCHEMBL7887240 | 0.81 | MEN1 (0.75) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 | |
| Indole-3-Acetic Acid SCHEMBL26344 | 0.81 | MEN1 (0.75) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 | |
| Indole-3-Acetic Acid SCHEMBL29350750 | 0.81 | MEN1 (0.75) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL24577957 | 0.80 | MAPT (0.68) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 | |
| Indole-3-Acetic Acid SCHEMBL468233 | 0.80 | MEN1 (0.73) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 | |
| Indole-3-Acetic Acid SCHEMBL31152574 | 0.80 | MEN1 (0.73) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 | |
| Indole-3-Acetic Acid SCHEMBL1375190 | 0.80 | MEN1 (0.73) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 | |
| Indole-3-Acetic Acid SCHEMBL11125791 | 0.80 | MEN1 (0.73) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526478-B1 | 3-INDOLYL THIOACETATE DERIVATIVES | MERRELL DOW PHARMA (US) | 1995-03-15 | — | — | EP | claimed |
| US-4617309-A | Sulfur-containing indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-10-14 | — | — | US | disclosed |