Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | FNTA | P49354 | 1/20 | 0.61 |
| ▸ | FNTB | P49356 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | AHR | P35869 | 1/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | MPO | P05164 | 2/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4628084 | 0.84 | MEN1 (0.58) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL3654754 | 0.83 | MEN1 (0.71) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL22302371 | 0.82 | MAPT (0.59) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| Indole-3-Acetic Acid SCHEMBL26344 | 0.81 | MEN1 (0.75) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| Indole-3-Acetic Acid SCHEMBL29350750 | 0.81 | MEN1 (0.75) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| Indole-3-Acetic Acid SCHEMBL7887240 | 0.81 | MEN1 (0.75) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL9161488 | 0.81 | MEN1 (0.65) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL10088137 | 0.81 | MEN1 (0.59) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL4628920 | 0.81 | PKM (0.57) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| Indole-3-Acetic Acid SCHEMBL1375190 | 0.80 | MEN1 (0.73) | MEN1KMT2AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773062-B2 | Deuterated compounds | SMALL PHARMA LTD (GB) | 2023-10-03 | — | — | US | disclosed |
| US-20230181530-A1 | DEUTERATED OR PARTIALLY DEUTERATED N,N-DIMETHYLTRYPTAMINE COMPOUNDS | SMALL PHARMA LTD. (GB) | 2023-06-15 | — | — | US | disclosed |
| US-11660289-B2 | Deuterated or partially deuterated N,N-dimethyltryptamine compounds | SMALL PHARMA LTD. (GB) | 2023-05-30 | — | — | US | disclosed |
| WO-2019154395-A1 | TETRAHYDROISOQUINOLINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | 中国科学院上海药物研究所 | 2019-08-15 | — | — | WO | disclosed |
| US-20120245213-A1 | HUMAN TYPE I TASTE RECEPTOR SUBUNIT 3 MODULATORS AND METHODS OF USING SAME | MOUNT SINAI SCHOOL OF MEDICINE | 2012-09-27 | — | — | US | disclosed |
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245213-A1 | HUMAN TYPE I TASTE RECEPTOR SUBUNIT 3 MODULATORS AND METHODS OF USING SAME | TAS1R3, TAS2R3, TAS1R1 | MEN1 602/4885KMT2A 4619/4885MAPT 4195/4885 |
| US-11660289-B2 | Deuterated or partially deuterated N,N-dimethyltryptamine compounds | TPH1, TPH2, HTR5A | MEN1 227/4885KMT2A 1418/4885MAPT 633/4885 |
| US-11773062-B2 | Deuterated compounds | PARK7, PSEN1, NDUFS5 | MEN1 440/4885KMT2A 2543/4885MAPT 431/4885 |
| US-20230181530-A1 | DEUTERATED OR PARTIALLY DEUTERATED N,N-DIMETHYLTRYPTAMINE COMPOUNDS | TPH1, TPH2, HTR5A | MEN1 227/4885KMT2A 1418/4885MAPT 633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.