Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.42 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158045 | 0.90 | PDE4B (0.50) | PDE4BNPSR1FYNKMT2AMEN1 | |
| SCHEMBL9586377 | 0.89 | PDE4B (0.49) | PDE4BNPSR1FYNKMT2AMEN1 | |
| SCHEMBL9159427 | 0.81 | PDE4B (0.49) | PDE4BTDP1NPSR1KDM4EHPGD | |
| SCHEMBL9165018 | 0.79 | PDE4B (0.40) | PDE4BNPSR1KMT2AMEN1MAPT | |
| SCHEMBL7014985 | 0.75 | KMT2A (0.71) | TDP1NPSR1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9159458 | 0.74 | PDGFRB (0.43) | PDE4BNPSR1KMT2AMEN1MAPT | |
| SCHEMBL9162880 | 0.72 | HSP90AA1 (0.45) | PDE4BNPSR1NPC1HPGDRAB9A | |
| SCHEMBL9157094 | 0.72 | MAPT (0.43) | PDE4BNPSR1KMT2AMEN1MAPT | |
| SCHEMBL10446488 | 0.72 | ALOX5AP (0.42) | NPSR1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9162981 | 0.72 | PDE4B (0.43) | PDE4BKMT2AALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354766-B1 | 5-substituted-2,4-diphenyl-pyrimidine derivatives, their production and herbicidal use | SUMITOMO CHEMICAL CO (JP) | 1993-11-03 | — | — | EP | claimed |
| US-5190575-A | 5-Methoxy- or -ethoxy, herbicides | SUMITOMO CHEMICAL CO., LTD. (JP) | 1993-03-02 | — | — | US | claimed |
| EP-0354766-A2 | 5-substituted-2,4-diphenyl-pyrimidine derivatives, their production and herbicidal use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-02-14 | — | — | EP | claimed |
| US-5403948-A | Treatment of 1-alkoxycarbonylthio-1-(trihaloalkylbenzoyl)-2-(n,n-dimethylamino)ethene with methyl iodide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-04-04 | — | — | US | disclosed |
| US-5349108-A | Chemical intermediates for nonphytotoxic herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-09-20 | — | — | US | disclosed |
| US-5270467-A | 5-substituted-2,4-diphenylpyrimidine derivatives | SUMITOMO CHEMICAL CO., LTD. (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0354766-B1 | 5-substituted-2,4-diphenyl-pyrimidine derivatives, their production and herbicidal use | SUMITOMO CHEMICAL CO (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5190575-A | 5-Methoxy- or -ethoxy, herbicides | SUMITOMO CHEMICAL CO., LTD. (JP) | 1993-03-02 | — | — | US | disclosed |
| EP-0354766-A2 | 5-substituted-2,4-diphenyl-pyrimidine derivatives, their production and herbicidal use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-02-14 | — | — | EP | disclosed |