Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9161561 | 0.90 | PDE4B (0.49) | PDE4BFYNALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9586377 | 0.90 | PDE4B (0.49) | PDE4BFYNALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9165018 | 0.88 | PDE4B (0.40) | PDE4BALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9159458 | 0.84 | PDGFRB (0.43) | PDE4BALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9159427 | 0.84 | PDE4B (0.49) | PDE4BFYNALDH1A1KMT2AMEN1 | |
| SCHEMBL9162880 | 0.82 | HSP90AA1 (0.45) | PDE4BALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9157094 | 0.82 | MAPT (0.43) | PDE4BALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9162981 | 0.81 | PDE4B (0.43) | PDE4BALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9160925 | 0.81 | HSD17B1 (0.45) | FYNALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14983665 | 0.70 | KCNH2 (0.47) | S1PR1DYRK1AKCNH2SCN10AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354766-B1 | 5-substituted-2,4-diphenyl-pyrimidine derivatives, their production and herbicidal use | SUMITOMO CHEMICAL CO (JP) | 1993-11-03 | — | — | EP | claimed |
| US-5190575-A | 5-Methoxy- or -ethoxy, herbicides | SUMITOMO CHEMICAL CO., LTD. (JP) | 1993-03-02 | — | — | US | claimed |
| US-5403948-A | Treatment of 1-alkoxycarbonylthio-1-(trihaloalkylbenzoyl)-2-(n,n-dimethylamino)ethene with methyl iodide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-04-04 | — | — | US | disclosed |
| US-5349108-A | Chemical intermediates for nonphytotoxic herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-09-20 | — | — | US | disclosed |
| US-5270467-A | 5-substituted-2,4-diphenylpyrimidine derivatives | SUMITOMO CHEMICAL CO., LTD. (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0354766-B1 | 5-substituted-2,4-diphenyl-pyrimidine derivatives, their production and herbicidal use | SUMITOMO CHEMICAL CO (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5190575-A | 5-Methoxy- or -ethoxy, herbicides | SUMITOMO CHEMICAL CO., LTD. (JP) | 1993-03-02 | — | — | US | disclosed |
| EP-0354766-A2 | 5-substituted-2,4-diphenyl-pyrimidine derivatives, their production and herbicidal use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-02-14 | — | — | EP | disclosed |