Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157094 | 0.83 | MAPT (0.43) | HSP90AA1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9159458 | 0.82 | PDGFRB (0.43) | HSP90AA1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9158045 | 0.82 | PDE4B (0.50) | ALDH1A1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL9162981 | 0.82 | PDE4B (0.43) | ALDH1A1CYP1A2CYP2C9CYP2C19HAVCR2 | |
| SCHEMBL9160925 | 0.82 | HSD17B1 (0.45) | HSP90AA1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9165018 | 0.78 | PDE4B (0.40) | ALDH1A1CYP1A2CYP2C9CYP2C19HAVCR2 | |
| SCHEMBL9159427 | 0.77 | PDE4B (0.49) | ALDH1A1KMT2AMEN1HPGDPDGFRB | |
| SCHEMBL9161561 | 0.72 | PDE4B (0.49) | ALDH1A1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL27773829 | 0.71 | DYRK1A (0.59) | ALDH1A1MAPTLMNAF2GLA | |
| SCHEMBL7037049 | 0.69 | GAPDH (0.52) | ALDH1A1MAPTLMNATP53GAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403948-A | Treatment of 1-alkoxycarbonylthio-1-(trihaloalkylbenzoyl)-2-(n,n-dimethylamino)ethene with methyl iodide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-04-04 | — | — | US | disclosed |
| US-5349108-A | Chemical intermediates for nonphytotoxic herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-09-20 | — | — | US | disclosed |
| US-5270467-A | 5-substituted-2,4-diphenylpyrimidine derivatives | SUMITOMO CHEMICAL CO., LTD. (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0354766-B1 | 5-substituted-2,4-diphenyl-pyrimidine derivatives, their production and herbicidal use | SUMITOMO CHEMICAL CO (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5190575-A | 5-Methoxy- or -ethoxy, herbicides | SUMITOMO CHEMICAL CO., LTD. (JP) | 1993-03-02 | — | — | US | disclosed |
| EP-0425247-A2 | 5-Substituted-2,4-diphenylpyrimidine derivatives, their production and herbicidal use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0354766-A2 | 5-substituted-2,4-diphenyl-pyrimidine derivatives, their production and herbicidal use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-02-14 | — | — | EP | disclosed |