⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790193 | 0.78 | — | — | |
| SCHEMBL9706249 | 0.73 | GAA (0.35) | — | |
| SCHEMBL721746 | 0.71 | — | — | |
| SCHEMBL18916912 | 0.71 | LMNA (0.33) | — | |
| SCHEMBL333701 | 0.71 | LMNA (0.33) | — | |
| SCHEMBL82328 | 0.71 | ALDH1A1 (0.52) | — | |
| SCHEMBL28879511 | 0.69 | LMNA (0.32) | — | |
| Ammonia Solution, Strong SCHEMBL3253047 | 0.69 | ALDH1A1 (0.50) | — | |
| SCHEMBL436035 | 0.69 | LMNA (0.32) | — | |
| SCHEMBL4412392 | 0.69 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420679-B1 | Acrylic block copolymer with crosslinkable silicon substituent | DU PONT (US) | 1995-02-22 | — | — | EP | claimed |
| EP-0420686-B1 | Hybrid acrylic star polymers with polysiloxane cores | DU PONT (US) | 1994-07-27 | — | — | EP | claimed |
| US-5057576-A | ACRYLIC BLOCK COPOLYMER WITH CROSSLINKABLE SILICON SUBSTITUENT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-15 | — | — | US | claimed |
| US-5036139-A | And attached to it at least four liner polyacrylate or poly-methacrylate arms; coatings, enamels | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-30 | — | — | US | claimed |
| US-5032647-A | Process for making hybrid acrylic star polymers with polysiloxane cores | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-16 | — | — | US | claimed |
| EP-0422805-A2 | Process for making hybrid acrylic star polymers with polysiloxane cores | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-17 | — | — | EP | claimed |
| EP-0420686-A2 | Hybrid acrylic star polymers with polysiloxane cores | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-03 | — | — | EP | claimed |
| EP-0420679-B1 | Acrylic block copolymer with crosslinkable silicon substituent | DU PONT (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5371147-A | Silicone-containing acrylic star polymers, block copolymers and macromonomers | PERMEABLE TECHNOLOGIES, INC. (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0420686-B1 | Hybrid acrylic star polymers with polysiloxane cores | DU PONT (US) | 1994-07-27 | — | — | EP | disclosed |
| US-5314961-A | Acrylic-silicone polymers | PERMEABLE TECHNOLOGIES, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| US-5314960-A | Silicone-containing polymers, oxygen permeable hydrophilic contact lenses and methods for making these lenses and treating patients with visual impairment | PERMEABLE TECHNOLOGIES, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0552306-A1 | NOVEL SILICONE-CONTAINING POLYMERS AND OXYGEN PERMEABLE HYDROPHILIC CONTACT LENSES THEREFROM | PERMEABLE TECHNOLOGIES, INC. (US) | 1993-07-28 | — | — | EP | disclosed |
| WO-1992007013-A1 | NOVEL SILICONE-CONTAINING POLYMERS AND OXYGEN PERMEABLE HYDROPHILIC CONTACT LENSES THEREFROM | PERMEABLE TECHNOLOGIES, INC. (US) | 1992-04-30 | — | — | WO | disclosed |
| US-5057576-A | ACRYLIC BLOCK COPOLYMER WITH CROSSLINKABLE SILICON SUBSTITUENT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-15 | — | — | US | disclosed |
| US-5036139-A | And attached to it at least four liner polyacrylate or poly-methacrylate arms; coatings, enamels | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-30 | — | — | US | disclosed |
| US-5032647-A | Process for making hybrid acrylic star polymers with polysiloxane cores | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0422805-A2 | Process for making hybrid acrylic star polymers with polysiloxane cores | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-17 | — | — | EP | disclosed |
| EP-0420679-A2 | Acrylic block copolymer with crosslinkable silicon substituent | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-03 | — | — | EP | disclosed |
| EP-0420686-A2 | Hybrid acrylic star polymers with polysiloxane cores | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-03 | — | — | EP | disclosed |