Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9159565 | 0.91 | HSP90AB1 (0.52) | NR4A2NPSR1KDM4EMAP4K4ALDH1A1 | |
| SCHEMBL9161172 | 0.90 | ALDH1A1 (0.52) | NR4A2NPSR1KDM4EALDH1A1CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL2249468 | 0.89 | ALDH1A1 (0.51) | NR4A2NPSR1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL9164555 | 0.86 | MAP4K4 (0.51) | NR4A2NPSR1KDM4EMAP4K4ALDH1A1 | |
| SCHEMBL9164875 | 0.82 | TSHR (0.56) | NR4A2KDM4EALDH1A1CA12CA1 | |
| SCHEMBL18658904 | 0.79 | NR4A2 (0.59) | NR4A2MAP4K4ALDH1A1CYP3A4LMNA | |
| SCHEMBL30155016 | 0.79 | NR4A2 (0.59) | NR4A2MAP4K4ALDH1A1CYP3A4LMNA | |
| SCHEMBL8835043 | 0.78 | NR4A2 (0.47) | NR4A2NPSR1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL28458986 | 0.77 | NR4A2 (0.58) | NR4A2ALDH1A1CYP3A4LMNACYP1A2 | |
| Ammonia Solution, Strong SCHEMBL2251166 | 0.77 | GRM5 (0.50) | NR4A2SOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354994-B1 | Quinoline derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5254565-A | Enzyme inhibitors; anticholesterol agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-19 | — | — | US | disclosed |
| EP-0354994-A2 | Quinoline derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-02-21 | — | — | EP | disclosed |