SCHEMBL9162003

SCHEMBL9162003

CC(C)CNC(=O)CCCCCC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.47
EPHX2 P34913 5/20 0.44
CYP2D6 P10635 2/20 0.41
CYP2C19 P33261 2/20 0.41
FAAH O00519 3/20 0.40
RECQL P46063 2/20 0.40
GAA P10253 1/20 0.40
EPHX1 P07099 1/20 0.39
ALDH1A1 P00352 1/20 0.38
MEN1 O00255 1/20 0.38
MAPK1 P28482 1/20 0.38
KMT2A Q03164 1/20 0.38
ASAH1 Q13510 1/20 0.38
CYP1A2 P05177 1/20 0.36
MMP1 P03956 1/20 0.36
MMP8 P22894 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9153250 1.00 HPGD (0.47) HPGDEPHX2CYP2D6CYP2C19FAAH
SCHEMBL17660269 0.93 HPGD (0.50) HPGDEPHX2CYP2D6CYP2C19RECQL
SCHEMBL16473882 0.85 CYP2D6 (0.46) HPGDEPHX2CYP2D6CYP2C19RECQL
SCHEMBL24450393 0.85 HPGD (0.38) HPGDEPHX2FAAHRECQLGAA
SCHEMBL24380532 0.85 FAAH (0.41) HPGDEPHX2FAAHRECQLGAA
SCHEMBL20034806 0.84 EPHX2 (0.47) HPGDEPHX2CYP2D6CYP2C19RECQL
SCHEMBL24490138 0.83 LMNA (0.50) HPGDFAAHRECQLALDH1A1
SCHEMBL24193602 0.81 CNR1 (0.43) HPGDEPHX2CYP2D6CYP2C19FAAH
SCHEMBL10814142 0.81 RECQL (0.38) HPGDFAAHRECQLGAAALDH1A1
SCHEMBL10633452 0.81 FAAH (0.48) EPHX2FAAHRECQLGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5391578-A Liquid state isomeric mixtures COLGATE-PALMOLIVE CO. (US) 1995-02-21 US disclosed