Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23902901 | 0.92 | ALDH1A1 (0.48) | TSHRDAOALDH1A1CYP2C19SGMS2 | |
| SCHEMBL891457 | 0.87 | ALDH1A1 (0.55) | TSHRALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL14893122 | 0.86 | ALDH1A1 (0.47) | TSHRALDH1A1CYP2C19SGMS2GAA | |
| SCHEMBL10485701 | 0.85 | ALDH1A1 (0.53) | TSHRALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL11932948 | 0.85 | TSHR (0.42) | TSHRDAOALDH1A1CYP2C19SGMS2 | |
| SCHEMBL11932932 | 0.82 | ALDH1A1 (0.41) | TSHRDAOALDH1A1CYP2C19GAA | |
| SCHEMBL13936102 | 0.80 | CYP2C19 (0.42) | TSHRDAOALDH1A1CYP2C19MAPT | |
| SCHEMBL9994936 | 0.79 | NOS3 (0.43) | DAOALDH1A1GAAMAPTCYP2D6 | |
| SCHEMBL29955505 | 0.79 | ALDH1A1 (0.42) | TSHRDAOALDH1A1CYP2C19GAA | |
| SCHEMBL18920913 | 0.79 | ALDH1A1 (0.40) | TSHRALDH1A1CYP2C19GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642866-B | Dihydrofuranquinoline derivative and synthesis method and application thereof | 广西师范大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-110642866-A | Dihydrofuranquinoline derivative and synthesis method and application thereof | 广西师范大学 | 2020-01-03 | — | — | CN | disclosed |
| US-9487602-B2 | Furan based resin, process for the preparation thereof, and use of the compound | DSM IP ASSETS B.V. (NL) | 2016-11-08 | — | — | US | disclosed |
| US-20130109822-A1 | FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND | DSM IP ASSETS B.V. (NL) | 2013-05-02 | — | — | US | disclosed |
| US-20110021740-A1 | FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND | DSM IP ASSETS B.V. (NL) | 2011-01-27 | — | — | US | disclosed |
| EP-2222656-A1 | FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND | DSM IP Assets B.V. (NL) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009077587-A1 | FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND | DSM IP ASSETS B.V. (NL) | 2009-06-25 | — | — | WO | disclosed |
| CN-1482122-A | Intermediates for producing 2-thiosubstituted carbapenems | 谷 | 2004-03-17 | — | — | CN | disclosed |
| CN-1136208-C | Intermediates for the preparation of 2-thiocarbpenems | 谷 | 2004-01-28 | — | — | CN | disclosed |
| CN-1223261-A | Novel 2-thiocarbpenems | AMERICAN CYANAMID CO (US) | 1999-07-21 | — | — | CN | disclosed |
| CN-1041633-C | Novel 2-thiocarbpenems | AMERICAN CRANAMID CO (US) | 1999-01-13 | — | — | CN | disclosed |