Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835043 | 0.86 | NR4A2 (0.47) | SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL2247727 | 0.84 | MAP4K4 (0.45) | HTR5AALOX5APFEN1 | |
| Ammonia Solution, Strong SCHEMBL2248185 | 0.84 | NR4A2 (0.46) | SMN1; SMN2 | |
| SCHEMBL8835094 | 0.83 | GRM2 (0.41) | CLK4SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL4775543 | 0.82 | GRM2 (0.41) | CLK4SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL2248963 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2 | |
| SCHEMBL9159755 | 0.82 | NCF1 (0.42) | — | |
| SCHEMBL8834931 | 0.80 | SMN1; SMN2 (0.36) | ALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL8835425 | 0.80 | MAPT (0.40) | CLK4SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL2247533 | 0.79 | MAPT (0.40) | CLK4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354994-B1 | Quinoline derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5254565-A | Enzyme inhibitors; anticholesterol agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-19 | — | — | US | disclosed |
| EP-0354994-A2 | Quinoline derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-02-21 | — | — | EP | disclosed |