Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 8/20 | 0.62 |
| ▸ | CA12 | O43570 | 7/20 | 0.62 |
| ▸ | CA1 | P00915 | 7/20 | 0.62 |
| ▸ | CA2 | P00918 | 7/20 | 0.62 |
| ▸ | CA4 | P22748 | 7/20 | 0.62 |
| ▸ | CA5A | P35218 | 7/20 | 0.62 |
| ▸ | CA7 | P43166 | 7/20 | 0.62 |
| ▸ | CA5B | Q9Y2D0 | 7/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL408020 | 0.90 | CA12 (0.69) | CA9CA12CA1CA2CA4 | |
| SCHEMBL8804099 | 0.83 | CA1 (0.58) | CA9CA12CA1CA2CA4 | |
| SCHEMBL7294894 | 0.80 | CA1 (0.59) | CA9CA12CA1CA2CA4 | |
| SCHEMBL9164159 | 0.74 | TDP1 (0.83) | CA9CA12CA1CA2CA4 | |
| SCHEMBL3079774 | 0.73 | L3MBTL1 (0.55) | CA9CA12CA1CA2CA4 | |
| SCHEMBL9163448 | 0.72 | L3MBTL1 (0.54) | CA9CA12CA1CA2CA4 | |
| SCHEMBL11384659 | 0.72 | LTA4H (0.57) | CA9CA1CA2TDP1L3MBTL1 | |
| SCHEMBL258266 | 0.70 | SRC (0.52) | CA9CA12CA1CA2CA4 | |
| SCHEMBL10798101 | 0.70 | LTA4H (0.55) | CA9CA1CA2TDP1L3MBTL1 | |
| SCHEMBL1050147 | 0.70 | KCNH2 (0.57) | CA9CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387353-A | Aryl diarenephosphinates, diaryl arenephosphonates, and arenephosphonothioates | THE DOW CHEMICAL COMPANY (US) | 1995-02-07 | — | — | US | disclosed |