Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | PAM | P19021 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.50 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL331714 | 0.98 | DGKA (0.57) | DGKACYP1A2PAMLMNAMEN1 | |
| Hexane SCHEMBL8603215 | 0.96 | DGKA (0.55) | DGKACYP1A2PAMLMNAMEN1 | |
| Dodecanol SCHEMBL29212179 | 0.94 | DGKA (0.64) | DGKACYP1A2PAMLMNAMEN1 | |
| Decanol SCHEMBL11043200 | 0.94 | DGKA (0.64) | DGKACYP1A2PAMLMNAMEN1 | |
| SCHEMBL29017540 | 0.94 | DGKA (0.64) | DGKACYP1A2PAMLMNAMEN1 | |
| Heptane SCHEMBL1238729 | 0.94 | DGKA (0.64) | DGKACYP1A2PAMLMNAMEN1 | |
| 1-Hexanol SCHEMBL1863211 | 0.94 | DGKA (0.59) | DGKACYP1A2PAMLMNAMEN1 | |
| Decanol SCHEMBL10945703 | 0.94 | DGKA (0.64) | DGKACYP1A2PAMLMNAMEN1 | |
| Hexane SCHEMBL5393961 | 0.94 | DGKA (0.64) | DGKACYP1A2PAMLMNAMEN1 | |
| Cetyl Alcohol SCHEMBL27937278 | 0.94 | DGKA (0.64) | DGKACYP1A2PAMLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373831-A1 | PROCESSES FOR THE PREPARATION OF ESTETROL AND INTERMEDIATES THEREOF | Newchem S.p.A. (IT) | 2024-05-29 | — | — | EP | disclosed |
| CN-117088928-A | Process for preparing high-purity estetrol | 湖北共同甾体药物研究院有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114302889-B | Industrial process for preparing high purity estetrol | 吉瑞工厂 | 2023-08-29 | — | — | CN | disclosed |
| US-11633406-B2 | Industrial process for the preparation of high purity estetrol | RICHTER GEDEON NYRT. (HU) | 2023-04-25 | — | — | US | disclosed |
| WO-2023001866-A1 | PROCESSES FOR THE PREPARATION OF ESTETROL AND INTERMEDIATES THEREOF | NEWCHEM S.P.A. (IT) | 2023-01-26 | — | — | WO | disclosed |
| EP-3877395-B1 | INDUSTRIAL PROCESS FOR THE PREPARATION OF HIGH PURITY ESTETROL | RICHTER GEDEON NYRT (HU) | 2022-12-07 | — | — | EP | disclosed |
| CN-114302889-A | Industrial process for the preparation of estetrol of high purity | 吉瑞工厂 | 2022-04-08 | — | — | CN | disclosed |
| EP-3877395-A1 | INDUSTRIAL PROCESS FOR THE PREPARATION OF HIGH PURITY ESTETROL | Richter Gedeon Nyrt. (HU) | 2021-09-15 | — | — | EP | disclosed |
| WO-2021044302-A1 | INDUSTRIAL PROCESS FOR THE PREPARATION OF HIGH PURITY ESTETROL | RICHTER GEDEON NYRT. (HU) | 2021-03-11 | — | — | WO | disclosed |
| EP-3287454-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2020-09-02 | — | — | EP | disclosed |
| CN-1956954-A | Novel androgens | ORGANON NV (NL) | 2007-05-02 | — | — | CN | disclosed |
| EP-1742912-A1 | NOVEL ANDROGENS | N.V. Organon (NL) | 2007-01-17 | — | — | EP | disclosed |
| EP-0812318-B1 | 4-AMINOTETRAHYDROBENZISOXAZOLE OR -ISOTHIAZOLE COMPOUNDS | LUNDBECK & CO AS H (DK) | 2006-02-08 | — | — | EP | disclosed |
| WO-2005102998-A1 | NOVEL ANDROGENS | N.V. ORGANON (NL) | 2005-11-03 | — | — | WO | disclosed |
| CN-1087290-C | 4-Aminotetrahydrobenzisoxazole or isothiazole compounds | LUNDBECK & CO AS H (DK) | 2002-07-10 | — | — | CN | disclosed |
| US-6174909-B1 | FOR TREATING ANALGESIA, PSYCHOSIS, CONVULSIONS, EPILEPSY, ANXIETY, MUSCULAR AND MOVEMENT DISORDERS, SPASTIC DISORDERS OR SYMPTOMS OF HUNTINGTON'S OR PARKINSONS DISEASE | H. LUNDBECK A/S (DK) | 2001-01-16 | — | — | US | disclosed |
| US-5998613-A | PSYCHOLOGICAL DISORDERS; ANALGESICS; ANTICONVULSANTS | H. LUNDBECK A/S (DK) | 1999-12-07 | — | — | US | disclosed |
| CN-1176638-A | 4-aminotetrahydrobenzisoxazole or-isothiazole compounds | LUNDBECK & CO AS H (DK) | 1998-03-18 | — | — | CN | disclosed |
| EP-0812318-A1 | 4-AMINOTETRAHYDROBENZISOXAZOLE OR -ISOTHIAZOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 1997-12-17 | — | — | EP | disclosed |
| WO-1996026929-A1 | 4-AMINOTETRAHYDROBENZISOXAZOLE OR -ISOTHIAZOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 1996-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11633406-B2 | Industrial process for the preparation of high purity estetrol | CYP17A1, HSD3B2, HSD3B1 | DGKA 1455/4885CYP1A2 28/4885PAM 3152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.