Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 5/20 | 0.40 |
| ▸ | BID | P55957 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153858 | 0.89 | KDM4E (0.58) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL7184449 | 0.85 | KDM4E (0.54) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL18685991 | 0.85 | KDM4E (0.56) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL9509076 | 0.83 | PPARA (0.54) | KDM4EALDH1A1MAPK1PPARAPPARG | |
| SCHEMBL3419303 | 0.83 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL18000031 | 0.80 | KDM4E (0.58) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL5176423 | 0.79 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL16719153 | 0.79 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL10966383 | 0.79 | TSHR (0.46) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL3130804 | 0.79 | PTGS2 (0.53) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589490-A | BENZAMIDE DERIVATIVES WITH NITROXY ALKYL GROUPS | ITALFARMACO S.P.A. (IT) | 1996-12-31 | — | — | US | disclosed |
| EP-0540544-B1 | BENZOIC ACID SUBSTITUTED DERIVATIVES HAVING CARDIOVASCULAR ACTIVITY | ITALFARMACO SPA (IT) | 1995-02-15 | — | — | EP | disclosed |
| US-5366992-A | IN MIXTURE WITH AN EXCIPIENT | ITALFARMACO S.P.A. (IT) | 1994-11-22 | — | — | US | disclosed |
| EP-0540544-A1 | BENZOIC ACID SUBSTITUTED DERIVATIVES HAVING CARDIOVASCULAR ACTIVITY. | ITALFARMACO SPA (IT) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001668-A1 | BENZOIC ACID SUBSTITUTED DERIVATIVES HAVING CARDIOVASCULAR ACTIVITY | ITALFARMACO S.P.A. (IT) | 1992-02-06 | — | — | WO | disclosed |