Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27581275 | 0.84 | KDM4E (0.52) | PTGS2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9426007 | 0.81 | ALDH1A1 (0.52) | PTGS2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28908922 | 0.81 | FOLH1 (0.50) | PTGS2TSHRSLC16A3 | |
| SCHEMBL7184449 | 0.80 | KDM4E (0.54) | PTGS2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL18685991 | 0.79 | KDM4E (0.56) | PTGS2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9163540 | 0.79 | KDM4E (0.52) | PTGS2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3419303 | 0.78 | KDM4E (0.55) | PTGS2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30846846 | 0.76 | PTGS2 (0.52) | PTGS2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9153858 | 0.75 | KDM4E (0.58) | PTGS2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL18000031 | 0.75 | KDM4E (0.58) | PTGS2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035047-A1 | BINARY COMPOSITIONS COMPRISING AN NO-DONOR AND AN A-SMASE INHIBITOR FOR THE TREATMENT OF RESPIRATORY DISEASES | PHARMAPATENTS GLOBAL LTD. (GB) | 2010-04-01 | — | — | WO | claimed |
| WO-2010035047-A1 | BINARY COMPOSITIONS COMPRISING AN NO-DONOR AND AN A-SMASE INHIBITOR FOR THE TREATMENT OF RESPIRATORY DISEASES | PHARMAPATENTS GLOBAL LTD. (GB) | 2010-04-01 | — | — | WO | disclosed |