SCHEMBL9163570

SCHEMBL9163570

CCOC(=O)NCCOc1ccc(Oc2cccc(Cl)c2)cc1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.45
FAAH O00519 1/20 0.44
TSHR P16473 3/20 0.44
HPGD P15428 2/20 0.44
LMNA P02545 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
MAPT P10636 2/20 0.44
EPHX2 P34913 1/20 0.43
PPARD Q03181 2/20 0.43
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.41
PKM P14618 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9162149 0.92 HRH4 (0.44) L3MBTL1FAAHTSHRHPGDLMNA
SCHEMBL9163534 0.91 POLB (0.46) L3MBTL1LMNASMN1; SMN2TDP1MAPT
SCHEMBL9163297 0.91 NPC1 (0.50) L3MBTL1HPGDLMNASMN1; SMN2TDP1
SCHEMBL9303588 0.90 L3MBTL1 (0.46) L3MBTL1FAAHTSHRLMNASMN1; SMN2
SCHEMBL9157608 0.90 L3MBTL1 (0.53) L3MBTL1TSHRHPGDLMNASMN1; SMN2
SCHEMBL9160000 0.90 MAPT (0.46) L3MBTL1FAAHTSHRHPGDLMNA
SCHEMBL9160265 0.89 HRH4 (0.43) L3MBTL1TSHRHPGDLMNASMN1; SMN2
SCHEMBL9156942 0.89 HPGD (0.45) L3MBTL1TSHRHPGDLMNASMN1; SMN2
SCHEMBL9158200 0.89 PPARA (0.48) L3MBTL1PPARDPPARGPPARAKMT2A
SCHEMBL9163309 0.89 PPARD (0.43) L3MBTL1FAAHTSHRHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460472-B1 Carbamic acid derivatives, their production and use SUMITOMO CHEMICAL CO (JP) 1995-03-08 EP claimed
US-5346920-A Insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-09-13 US claimed
EP-0460472-A1 Carbamic acid derivatives, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-12-11 EP claimed
EP-0460472-B1 Carbamic acid derivatives, their production and use SUMITOMO CHEMICAL CO (JP) 1995-03-08 EP disclosed
US-5346920-A Insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-09-13 US disclosed
EP-0460472-A1 Carbamic acid derivatives, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-12-11 EP disclosed